Weather and climate extremes in light of the IPCC SREX (2011) and beyond.The recent IPCC Special Report (IPCC SREX, 2011) provides a comprehensive overview Makeup of meteorological (i.e.weather and climate) extremes and their various aspects.The present paper reflects the core concepts of the Report, clarifying the relations of the natural and anth
Abstract Objectives Leflunomide (LEF) is a conventional synthetic disease-modifying antirheumatic drug and suppresses T-cell proliferation and activity by inhibiting pyrimidine synthesis using dihydroorotase dehydrogenase (DHODH); however, several studies have demonstrated that LEF possesses anticancer and antiangiogenic effects in some malignant t
Gastric retentive dosage forms are highly useful for the delivery of many kinds of drugs.The use of floating dosage forms (FDFs) is one of the methods used to achieve prolonged gastric residence time (GRT).Formulation of Metronidazole (MDZ) as FDF provides an opportunity for both local and systemic drug action for eradication of Helicobacter pylori